Ingredient Science

THCV (Tetrahydrocannabivarin)

THCV is often called the “diet cannabinoid” for its unique effect on appetite regulation. It acts as a CB1 receptor antagonist, which may suppress appetite, in contrast to THC, which stimulates it.
Scientific Insight:

  • In animal studies, THCV has been shown to reduce food intake and increase energy expenditure.
  • It may improve glucose tolerance and insulin sensitivity, both key to weight and metabolic health.
  • THCV may also influence dopaminergic pathways, enhancing motivation and focus without intoxication.

Sources:

Jadoon KA et al., Diabetes Care (2016)

Wargent ET et al., British Journal of Pharmacology (2013)

 

CBC (Cannabichromene)

CBC doesn’t bind strongly to CB1 or CB2 receptors but enhances endocannabinoid function by inhibiting FAAH, the enzyme that breaks down anandamide, a key mood-stabilizing molecule.
Scientific Insight:

  • CBC shows anti-inflammatory effects by acting on TRPA1 receptors, which are involved in pain and inflammation signaling.
  • It may also stimulate neurogenesis in certain brain regions, supporting mood and cognitive resilience.

Sources:

De Petrocellis et al., British Journal of Pharmacology (2011)

Shinjyo et al., Neurochemistry International (2013)

CBGa (Cannabigerolic Acid)

Known as the “mother of all cannabinoids,” CBGa is the precursor to THC, CBD, and CBC. While less studied in isolation, emerging research suggests its key role in metabolic regulation and gut health.
Scientific Insight:

  • CBGa may modulate PPAR receptors, which play roles in fat metabolism and insulin sensitivity.
  • It exhibits antioxidant and anti-inflammatory effects, making it a candidate for gut and immune support.

Sources:

D’Aniello et al., Cellular Physiology and Biochemistry (2021)

Nachnani R et al., Biomedicine & Pharmacotherapy (2021)

Functional Mushrooms – Why We Use This

Lion’s Mane (Hericium erinaceus)

Lion’s Mane contains hericenones and erinacines, compounds that stimulate nerve growth factor (NGF), which is vital for brain cell growth, repair, and protection.
Scientific Insight:

  • Clinical trials show it can improve memory and cognitive function in mild cognitive impairment.
  • It may reduce anxiety and depression symptoms by modulating neuroplasticity and inflammation.

Sources:

Mori K et al., Phytotherapy Research (2009)

Nagano M et al., Biomedical Research (2010)

Cordyceps (Cordyceps militaris)

Cordyceps enhances energy by increasing cellular ATP production, which fuels all metabolic activity. It also supports oxygen utilization and endurance.
Scientific Insight:

  • Shown to boost VO2 max and reduce fatigue in both athletes and sedentary individuals.
  • Acts on AMPK pathways, which regulate metabolism and fat oxidation.

Sources:

Chen S et al., Journal of Alternative and Complementary Medicine (2010)

Koh JH et al., Journal of Nutritional Science and Vitaminology (2003)

Nutraceuticals – Show Me Benefits

L-Theanine

An amino acid found in tea, L-Theanine promotes alpha brain wave activity, which is associated with relaxed alertness.
Scientific Insight:

  • Enhances focus and cognitive performance when combined with caffeine.
  • Reduces stress-induced cortisol levels and helps prevent caffeine overstimulation.

Sources:

Haskell CF et al., Nutritional Neuroscience (2008)

Kimura K et al., Biological Psychology (2007)

L-Carnitine

A naturally occurring compound that helps transport long-chain fatty acids into mitochondria, where they’re burned for energy.
Scientific Insight:

  • Supports fat metabolism, physical performance, and recovery.
  • Shown to reduce muscle soreness and improve endurance in clinical studies.

Sources:

Broad EM et al., International Journal of Sport Nutrition (2005)

Malaguarnera M et al., American Journal of Clinical Nutrition (2007)

Caffeine

A well-known stimulant that enhances focus and alertness. When paired with L-Theanine, the effect becomes smoother and more sustained.
Scientific Insight:

  • Stimulates dopamine and norepinephrine, improving mood, motivation, and cognitive function.
  • Enhances reaction time, alertness, and physical endurance.

Sources:

Smith A et al., Human Psychopharmacology (2002)

Kennedy DO et al., Biological Psychology (2008)

Green Tea Extract (EGCG)

Green tea extract is rich in epigallocatechin gallate (EGCG), a catechin that boosts metabolism and supports antioxidant defenses.
Scientific Insight:

  • Increases thermogenesis and fat oxidation, particularly during low-intensity exercise.
  • Delivers cellular protection through strong antioxidant activity.

Sources:

Hursel R et al., Obesity Reviews (2009)

Cabrera C et al., Journal of the American College of Nutrition (2006